New Publication: AI-Based Diagnosis of Coronary Heart Disease — A Focus on the Cardio Explorer®
Originally published on explorishealth.com
In Germany, mortality from cardiovascular disease is disproportionately high compared to other countries. At the same time, it has one of the highest rates of coronary angiography in the world.
This paradoxical situation is analyzed in depth in the recent review "Coronary Heart Disease—A German Paradox" by Remppis et al.
The central problem: The guideline models used to date to estimate the pretest probability (PTP) of coronary heart disease (CHD) are imprecise and therefore unsuitable for efficiently managing the diagnostic pathway.
The selection of appropriate diagnostic methods—both noninvasive and invasive—essentially depends on the individually calculated PTP; its accurate determination is the key step toward efficient and patient-friendly treatment.
For the first time, Cardio Explorer® enables personalized PTP based on clinical data and 15 laboratory parameters. The publication shows that, with a diagnostic accuracy (AUC) of 0.87, Cardio Explorer® achieves performance on par with imaging procedures—and enables significant cost savings.
The authors emphasize that AI-based tools such as Cardio Explorer® help ensure consistent implementation of the logic behind the ESC 2024 guidelines: avoiding unnecessary diagnostic steps, stratifying patients in a more targeted manner, and using valuable healthcare resources more efficiently.
AI-based precision diagnostics is the key to sustainable, evidence-based, and patient-centered cardiac medicine.
🔗 About the publication: Remppis BA et al. (2025): Coronary heart disease—a German paradox. Using AI-based technology to solve a relevant clinical problem. Pacemaker Therapy + Electrophysiology. DOI: 10.1007/s00399-025-01094-6
Are you interested in how Cardio Explorer® applies to your coronary pathway? Our team would be happy to walk you through the platform and the evidence behind it.
