Understand disease through biology.

We use AI to decode the biological signals that drive disease, starting with coronary artery disease.

ISO 13485

ISO 27001

The science

It's in their blood

Coronary artery disease leaves measurable traces in routine clinical chemistry. Cardio Explorer® reads these biological signals and translates them into a personalized assessment of the likelihood of obstructive disease.

Individualized, sex-specific pre-test probability based on routine blood chemistry tests
No new tests or sampling: signals extracted from data that has already been collected
Validated against invasive coronary angiography across European cohorts

Clinical evidence

More than a decade of peer-reviewed evidence

An ongoing research program: from the foundational diagnostic algorithm to independent validation across Europe and a prospective implementation study currently underway.

Explore the clinical evidence

Clinical StudiesFrom algorithm development through validation for intended use.

CountriesSwitzerland, Germany, and the Netherlands.

>4,500

PatientsAcross retrospective cohorts and ongoing prospective evaluations.

SHIFT

The Future of Coronary Artery Disease Care

A normal ECG and troponin levels rule out an acute myocardial infarction—but not obstructive coronary artery disease. As a result, many patients with clinically significant CAD are discharged from the hospital undiagnosed. Cardio Explorer® changes that.

Hidden Disease

In a landmark cohort study of patients with chest pain, approximately 1 in 10 patients who were initially cleared after routine evaluation were subsequently found to have obstructive CAD.¹View clinical evidence

Made visible

Cardio Explorer® analyzes routine clinical and laboratory data already collected during patient care—requiring no additional tests and no changes to the workflow—to identify patients whose obstructive CAD would otherwise go undetected.Explore the product

Better decisions

Patients identified by Cardio Explorer® can be referred for appropriate follow-up testing or catheterization at an earlier stage, improving patient selection and increasing the diagnostic yield of the catheterization laboratory.View clinical evidence

Obstructive CAD Non-obstructive CAD

1.Hoffmann U, et al. Coronary CT angiography versus standard evaluation in acute chest pain (ROMICAT-II). N Engl J Med. 2012;367(4):299–308. doi:10.1056/NEJMoa1201161

Integration

Built into the systems your team already uses

Cardio Explorer® runs natively within Dedalus ORBIS, using routine data that has already been captured—no new tests, no new documentation, no new workflow.

Using a different clinical information system? Contact our team.

Reach out

Your EMR

OUTCOMES

Outcomes That Matter

Cardio Explorer® is designed to help identify patients with clinically significant coronary artery disease at an earlier stage and to support a more strategic allocation of cardiovascular resources.

Identify

More actionable CAD identified

Identify patients with clinically significant coronary artery disease who might otherwise remain undiagnosed.

Prioritize

Higher-yield coronary pathways

Increase the proportion of patients who undergo advanced imaging and invasive evaluation and are found to have actionable disease.

Optimize

Better use of scarce cardiovascular resources

Focus specialist time, imaging capacity, and cath lab utilization where they can have the greatest clinical impact.

Voices from the Field

Built with the teams that provide cardiac care

We believe Cardio Explorer®, Exploris Health's innovative cardiac test, will significantly improve care for patients with suspected coronary artery disease.

Thomas Helms, M.D.

Chairman of the Board, German Foundation for the Chronically Ill

Cardio Explorer® achieves over 95% accuracy in calculating individualized and sex-specific pre-test probabilities and enables significantly better patient management than any other solution currently available on the market.

Prof. Bjoern Remppis

Interventional Cardiologist, Bad Bevensen Heart and Vascular Center

This is certainly an important step forward and holds great potential for the entire diagnostic process for coronary artery disease.

Prof. Hans-Peter Brunner-La Rocca

Vice Chair, Department of Cardiology — Director, Heart Failure Clinic, Maastricht University Medical Center

From data to diagnostic confidence. The Cardio Explorer® harnesses the full potential of available patient data to safely rule out coronary artery disease.

Michael Zellweger, M.D.

Professor of Cardiology — Head of Cardiac Imaging, Department of Cardiology, University Hospital Basel, Switzerland